Tumor necrosis factor a, TNFa, is an inflammatory mediator that has been shown to be elevated in patients with low back pain. Is there a treatment available for it?

A recent study showed that TNFa is present in a much greater proportion of people with chronic low back pain versus those without. Presently there is no specific treatment to target TNFa. There are anticytokine therapies available but none specifically aimed at lowering TNFa levels.

H. Wang, M. Schiltenwolf, M. Buchner. The role of TNFa in patients with chronic low back pain: A prospective comparative longitudinal study. Clin J Pain. 2008. Vol. 24, Num. 3. Pp. 273-278.



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